Nasopharyngeal carcinoma in children.

نویسندگان

  • M Werner-Wasik
  • P Winkler
  • A Uri
  • J Goldwein
چکیده

asopharyngeal carcinoma is rare in children and adolescents. Nevertheless, it is considered to be Ihe only tumour of surface epithelium afflicting children and young adults. Three such cases seen om a period of eight years (1990-1997) are reported with a review of relevant literature. sopharyngeal carcinoma IS not an uncommon of head and neck region in adults, more so in the risl areas of Southern China, Hong Kong etc. ,I second peak in age incidence in the second ,has been observed in non-endemic areas (4), the nceofthe tumour in childhood is very rare (6). It been eslimated that 5 % of primary malignant I> in children originate in the area of head and 191. while nasopharyngeal carcinoma constitutes :!%ofhead and neck malignant tumours in children Rel,,"nce of these statistics is evident not only "selhe nasopharyngeal cancer has been considered ,only tumour of surface epithel ium affl icting ~ren and young adults (14) but also because the OSIS of this rare tumour may be delayed being ed by more frequent problems of childhood, such n!eclions of the upper respiratory tract or oth,?r lbt Department of E.N.T. & ·Oepartment of Pathology, Government Medical College, Srinagar-190 010 (J&K) India ""pond,nee to: Dr. Rauf Ahmad, 177 Nursing Garh, Srinagar-t'JO 010 (J&K) INDIA \0 2. April-June 1999 21 '..,JK SCIENCE __________ ~.:;';. __iioiiiiiio......... ..... margins and somewhat restricted mobility lIiI under the angle of mandible on right side. \, Iymphnodes were enlarged. Rest ofE.N.T. exam, was unremarkable. Posterior rhinoscopy could completed. Fine needle aspiration orthe swellin. inconclusive and 3n incisional biopsy underge anaesthesia was planned. Under anaesth nasopharyngoscopy was first performed, revealed an ulcero-proliferative growth on lateral nasopharyngeal wall Biopsy was taken: the growth. Fig. 2. Patient presented wilh unilalcnll upper deep WI Iylllphnode enlargment only. Biopsy was rep0l1ed as undifferentiated squamolli carcinoma. Repeat FNAC of neck swelling rei secondary deposits in the lymph nodes of neck.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Acute Lymphoblastic Leukemia Following Nasopharyngeal Carcinoma: Report of an Unusual Case

Introduction: Nasopharyngeal carcinoma (NPC) is a rare malignancy in children. Nasal obstruction, otitis media with effusion, pain in the ear, hearing problems, and unusual neck mass are among the signs and symptoms of this malignancy.   Case Report: We report the case of a 13-year-old girl with NPC who later developed acute lymphoblastic leukemia (ALL) through the course of her disease. To our...

متن کامل

Rad51 Expression in Nasopharyngeal Carcinoma and Its Association with Tumor Reduction: A Preliminary Study in Indonesia

Background: Overexpression of Rad51 protein in many tumor cells has been proven to increase radioresistance and can be related to the resistance of chemosensitivity of tumor cells. This preliminary study was conducted to determine the relationship between the Rad51 expression level in nasopharyngeal carcinoma and the response of the treatment based on the measurement o...

متن کامل

Dose Measurements of Parotid Glands and Spinal Cord in Conventional Treatment of Nasopharyngeal Carcinoma Using RANDO Phantom and Thermoluminescent Dosimeters

Introduction Radiotherapy is regarded as the first treatment of choice for nasopharyngeal carcinoma. Despite the advantages of radiotherapy, patients may suffer from a wide range of side-effects due to the presence of many sensitive normal tissues in these regions. If the absorbed dose exceeds the tolerance level in parotid glands and the spinal cord, myelopathy, Lhermitte's sign and xerostomia...

متن کامل

Nasopharyngeal Carcinoma with Cystic Cervical Metastasis Masquerading as Branchial Cleft Cyst: A Potential Pitfall in Diagnosis and Management

Introduction:Most metastatic lymph nodes from head and neck malignancy are solid. Cystic nodes are found in 33% - 61% of carcinomas arise from Waldeyer’s ring, of which only 1.8% - 8% originate are from the nasopharynx. Some cystic cervical metastases were initially presumed to be branchial cleft cyst. This case report aims to highlight the unusual presentation of cystic cervical metastasis sec...

متن کامل

The importance of the optimal volume in the treatment of locally recurrent nasopharyngeal carcinoma; brachytherapy or stereotactic radiotherapy?

Introduction: Nasopharyngeal carcinoma (NPC) is commonly known as a radiosensitive tumor with the initial good response to radiation. Despite the improved outcome in loco regional control by the introduction of combining treatment, modern radiotherapy techniques and enhanced imaging studies, local recurrent after primary treatment with rate ranges from 15-58% in 5 years, stil...

متن کامل

Radiobiological Model-Based Comparison of Three-Dimensional Conformal and Intensity-Modulated Radiation Therapy Plans for Nasopharyngeal Carcinoma

Introduction: Radiobiological modeling of radiotherapy plans are used for treatment plan comparisons. The current study aimed to compare the three-dimensional conformal radiation therapy (3DCRT) and intensity-modulated radiation therapy (IMRT) plans for nasopharyngeal cancer using radiobiological modeling. Materials and Methods: This study was conducted on 10 patients with nasopharyngeal carci...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Medical and pediatric oncology

دوره 26 5  شماره 

صفحات  -

تاریخ انتشار 1984